People who suffer from narcolepsy and cataplexy tend to engage more frequently in risky behaviors, such as substance use disorder. Substance use disorder can worsen the symptoms of narcolepsy.
Narcolepsy
Narcolepsy is a sleep condition that presents itself as overwhelming daytime drowsiness and causes a person to fall asleep all of a sudden. A person suffering from narcolepsy will find it hard to stay awake for prolonged periods of time. This disorder causes a person to experience serious disruptions in their everyday life because they are unable to function normally.
According to UCLA Health, narcolepsy affects about 1 in 2,000 to 3,000 people but can go undiagnosed for years. The exact cause of narcolepsy is unknown. It is believed that low levels of a neurotransmitter known as orexin or hypocretin are involved in wakefulness and contribute to narcolepsy. It is also believed that genetics and other risk factors play a role. Risk factors include a person’s age, autoimmune disorders, brain injuries, and family history. Narcolepsy typically begins in people between 10 and 30 years old. If you have a family history of narcolepsy your risk for also getting it is 20 to 40 times more. Narcolepsy side effects include excessive daytime sleepiness, cataplexy, sleep paralysis, changes in rapid eye movement (REM) sleep, and hallucinations. People who suffer from narcolepsy will fall asleep without warning, anywhere, and anytime. They also experience decreased alertness and focus throughout the day. Excessive sleepiness is typically the first symptom to appear and is the most troublesome because it makes it extremely hard for a person to focus and fully function. People who suffer from narcolepsy may experience cataplexy, which is the sudden loss of muscle tone. It can cause a bunch of different physical changes such as slurred speech and complete weakness of most muscles that can last up to a couple of minutes. This condition is uncontrollable and is often triggered by intense emotions such as laughter, excitement, fear, surprise, and anger. Sleep paralysis is another side effect of narcolepsy. A person with narcolepsy may experience a sudden inability to move or speak while they are falling asleep or waking up. Not everyone who experiences this symptom will have narcolepsy. A lot of people who don’t have narcolepsy experience sleep paralysis at some point in their lives. REM sleep is when people experience dreams. In people who suffer from narcolepsy, it can occur at any point during the day. A person who has narcolepsy will transition quickly to REM sleep, typically within 15 minutes of falling asleep. Hallucinations are another side effect of narcolepsy. The type of hallucinations a person with narcolepsy experiences is known as hypnagogic hallucination and hypnopompic hallucination. Hypnagogic hallucination usually happens as a person is falling asleep. Hypnopompic hallucinations occur as a person is waking up. These hallucinations are frightening because a person might not be fully asleep when they begin dreaming and will experience their dreams as reality.
Narcolepsy Side Effects
Excessive Daytime Sleepiness
Cataplexy
Sleep Paralysis
Changes in REM Sleep
Hallucinations
Additional Effects of Narcolepsy
Additional long term effects of narcolepsy are fragmented sleep and insomnia as well as automatic behaviors. Individuals who suffer from narcolepsy are not only very sleepy during the day, but also experience difficulties staying asleep at night. These sleep disturbances at night can include vivid dreaming, insomnia, sleep apnea, acting out while dreaming, and leg movements.
Automatic behaviors occur when a person falls asleep during an activity for a few seconds and continues on with the activity without being consciously aware of what they are going. For example, a person might fall asleep writing and continue to write even though they are not aware they are doing it. Their handwriting will have deteriorated and they will not be able to recall their actions.
Narcolepsy and Addiction
Numerous studies point to associations between narcolepsy and addition. For example, an article published in the Journal of Clinical Sleep Medicine found that people who were diagnosed with narcolepsy and had cataplexy were a lot more likely to be impulsive than those who did not have cataplexy. This is because hypocretin, which is used to help keep people awake and mediate addiction and reward-seeking behaviors in the brain is often lower in people who suffer from narcolepsy. Therefore, these individuals are more likely to engage in risk-taking behaviors, such as substance use disorder.
Another article published in Sleep mentioned that decision making is a key function in real-life situations, and changes in the brain’s reward processing system create a risk for the development of impulsivity and substance use disorder. The study also mentioned that people who experience narcolepsy with cataplexy tend to prefer risky choices, which can result in increased use of alcohol and other drugs.
Narcolepsy and Marijuana
According to an article published in the Journal of Clinical Sleep Medicine, 43 percent of children with urine drug screens positive for marijuana actually had test results consistent with narcolepsy or abnormal REM sleep patterns. No child younger than 13 years old has a positive urine drug screen. The study also found that males were more likely to have a positive urine drug screen and findings consistent with narcolepsy. The study suggested that narcolepsy without cataplexy in older adolescents could be related to unreported marijuana use, abuse of sedatives, or other illegal drugs.
Narcolepsy and Alcohol
An interesting finding from a study published in Sleep, found that an increased proportion of alcohol and tobacco users experienced narcolepsy. The study mentioned that tobacco is a cognitive enhancer so it is likely that people smoke tobacco to help alleviate signs of sleepiness and used it as a self-treatment for the stimulant effects of nicotine. Therefore, it appears that people who experience narcolepsy may use tobacco to self-treat their symptoms. This research study indicates there is an association between narcolepsy and alcohol as well as tobacco use.
Heavy use of alcohol can result in alcohol-induced narcolepsy. According to a case report published in the Shanghai Archives of Psychiatry, chronic heavy alcohol use can cause a lot of damage to the central nervous system and can also cause narcolepsy. The case study indicated that chronic alcohol use can inhibit a person’s central nervous system which can result in narcolepsy.
Additionally, the effects of alcohol on narcolepsy are vast. Alcohol can worsen the symptoms of narcolepsy. It can disrupt your sleep, increase a person’s fatigue, frequent sleep interruptions, and sleep paralysis. Therefore, it is recommended that a person avoids drinking alcohol before or close to the bed. Even though alcohol may make you feel drowsy, it makes you more likely to wake up during the night and worsens your quality of sleep. If you did not sleep well you will be more likely to experience narcolepsy symptoms the next day.
Addiction and Narcolepsy Treatment
While there is currently no cure for narcolepsy, medications, and lifestyle changes can help a person manage their symptoms. Also, gaining support from family, friends, employers, and teachers can help you cope with narcolepsy.
The treatment of narcolepsy is mainly geared towards suppressing the symptoms and improving a person’s quality of life to help them stay as alert as possible during the day. The most common treatment methods include stimulants and behavioral therapy to reduce acute daytime drowsiness, antidepressants to decrease episodes of cataplexy and other REM-related symptoms, and sedatives to improve the quality of sleep. One drug used to treat narcolepsy is modafinil. This is a stimulant that is used to promote wakefulness and rescue excessive daytime sleepiness. Additional treatment includes nap therapy, maintaining a proper diet, and regular exercise.
A person who experienced narcolepsy might be more likely to engage in risk-taking behaviors, such as substance use and abuse. As mentioned above, alcohol abuse can actually worsen symptoms of narcolepsy. Therefore, if you or someone you love is suffering from addiction, finding a high-quality rehab clinic can provide the support needed to overcome your addiction. This can actually help you better manage your narcolepsy by reducing substance use disorder-related symptoms.
References
- Addiction Treatment Options. Sunshine Behavioral Health.
- Changes in brain cells linked to opiate addiction, narcolepsy. UCLA Health.
- Effects of psychostimulants on impulsivity and risk taking in narcolepsy with cataplexy. Sleep.
- Narcolepsy UK.
- Narcolepsy. John Hopkins Medicine.
- Narcolepsy. Mayo Clinic.
- Narcolepsy Fact Sheet. National Institute on Neurological Disorders and Stroke.
- Narcolepsy Treatment. The National Sleep Foundation.
- Narcolepsy induced by chronic heavy alcohol consumption: A case report. Shanghai Archives of Psychiatry.
- Reward-seeking behavior in human narcolepsy. Journal of Clinical Sleep Medicine.
- Smoking, alcohol, drug use, abuse, and dependence in narcolepsy and idiopathic hypersomnia: A case-control study. Sleep.
- Urine toxicology screen in multiple sleep latency tests: The correlation of positive tetrahydrocannabinol, drug negative patients, and narcolepsy. Journal of Clinical Sleep Medicine.
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